The goal of this Community Guide systematic review was to examine the effectiveness of team-based care in improving blood pressure (BP) outcomes. Results suggest that team-based care is effective in improving BP outcomes. From the update, the proportion of patients with controlled BP improved (median increase ¼ 12 percentage points); systolic BP decreased (median reduction ¼ 5.4 mmHg); and diastolic BP also decreased (median reduction ¼ 1.8 mmHg). Team-based care increased the proportion of people with controlled BP and reduced both systolic and diastolic BP, especially when pharmacists and nurses were part of the team. Implementation of this multidisciplinary approach will require health system–level organizational changes and could be an important element of the medical home.