In March of 2016, the Office of the Special Envoy for Health in Agenda 2030 and for Malaria, in partnership with the Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai, convened a Task Force of key stakeholders and leaders in the global and domestic development of CHW programs with the purpose of developing a framework for sustainable, effective CHW programs in the U.S. This Report draws on the experience of those leaders in an effort to provide practical guidance on planning and implementing the programmatic, operational, and financial needs of CHW programs. Our intent is to provide a framework to guide local community and healthcare leaders as they develop sustainable programs to suit the health needs of their communities.